"Raphael offers rational worship to God on behalf of Tobit and Sara. For after they had prayed, the prayer of them both, says the Scripture, was heard. 'The prayer of them both (was heard) before the majesty of the mighty Raphael and he was sent to heal them both' (Tobit 3.16-17)."
(Origen, ca. 233, On Prayer 11:1, in Popular Patristics 29:134)