Is there even a difference between a real universe created by God and a virtual reality created by God?
Only if you choose the red pill over the blue pill.
But to address your question seriously, in what sense could we even say the world was virtual and not real? We would have to be "outside" the world to even understand what they meant.
Also, I have a small quibble about the title of the thread and the video. That title equates "digital" with "virtual". I realize that in common parlance, the most common application of the word "digital" is to computers and the Internet, which suggests a "virtual" world. But in fact there is no necessary connection between virtual and digital. There were analog computers before their were digital computers, and there were analog simulations before their were digital simulations. So you can have a "virtual" reality that isn't digital. Conversely, there are some instances of a "digital" reality in the real world. Anything with separate discrete states is "digital". That includes stair steps, photo-receptors in animal eyes making images from pixels, and discrete atomic states like atomic number. So you can have digital without virtual and virtual without digital. So the title should have been "Virtual argument for...." But I see I have spent way too many words on what is essentially a small quibble. Sorry.