From the dripping Faucit; Chloroquine is a potent inhibitor of SARS coronavirus infection and spread.

Bonnie

Super Member
Who said it was?

The 2005 HCQ study was on SARS--noy covid-19, which did not exist then.
You have no medical lab experience.

So? But I can read articles by those who do.
None. And you are not prepared to understand the pathogens.
Oh I can understand enough to know that SARS And Covid-19 are not the same disease. And I can certainly understand that the first clause in your OP had 2 errors--that Virology journal is NOT the official publication of the NIH--The NIH Catalyst is. Nor is the NIH "Fauci's"--Fauci is the director of the NIAID, one of 27 departments within the NIH.

Two inaccuracies right off the bat in your OP. The source you quoted could not even get those things straight. My journalism teachers called those "fatal mistakes."
 

Authentic Nouveau

Well-known member
The 2005 HCQ study was on SARS--noy covid-19, which did not exist then.


So? But I can read articles by those who do.

Oh I can understand enough to know that SARS And Covid-19 are not the same disease. And I can certainly understand that the first clause in your OP had 2 errors--that Virology journal is NOT the official publication of the NIH--The NIH Catalyst is. Nor is the NIH "Fauci's"--Fauci is the director of the NIAID, one of 27 departments within the NIH.

Two inaccuracies right off the bat in your OP. The source you quoted could not even get those things straight. My journalism teachers called those "fatal mistakes."
So you can't discuss the virus. You need Fake checkers as a crutch to bludgeon people you can't stand.

Why are you making stuff up?

You know nothing about clinical virology. You have never even taken micro.

You were judging Some tucker dude on Fox

Judgmentalism.

Small rural Lutheran church pastor's wives are not prepared to do lab work and discuss.

From my Professional Psych credentials you are protecting your ego.

From medicine,
You don't understand this and have no clue how the Ammonium chloride and C18H26ClN3 operate inside the liposomes.

Since chloroquine inhibited SARS-CoV infection when added before or after infection, we hypothesized that another common lysosomotropic agent, NH4Cl, might also function in a similar manner. Ammonium chloride has been widely used in studies addressing endosome-mediated virus entry. Coincidently, NH4Cl was recently shown to reduce the transduction of pseudotype viruses decorated with SARS-CoV spike protein In an attempt to examine if NH4Cl functions similarly to chloroquine, we performed infection analyses in Vero E6 cells before (Fig. and after they were treated with various concentrations of NH4Cl. In both cases, we observed a 93–99% inhibition with NH4Cl at ≥ 5 mM. These data indicated that NH4Cl (≥ 5 mM) and chloroquine (≥ 10 μM) are very effective in reducing SARS-CoV infection. These results suggest that effects of chloroquine and NH4Cl in controlling SARS CoV infection and spread might be mediated by similar mechanism(s).

I won't go into the transport vehicle since you are not prepared to discuss science.

Fauchi is not completely ignorant. He is deceptive. You missed the 2 lines where he mentioned the width of the spectrum.

For C18H26ClN3O
Has more than 1 function.

As a lysosomotropic agent, hydroxychloroquine raises intralysosomal pH, impairing autophagic protein degradation; hydroxychloroquine-mediated accumulation of ineffective autophagosomes may result in cell death in tumor cells reliant on autophagy for survival.

I can see right thru your political games and science outsider political agenda.
 
Last edited:

Whateverman

Well-known member
From medicine, You don't understand this and have no clue how the Ammonium chloride and C18H26ClN3 operate inside the liposomes.
Copy paste alert!

You have no training in fact-gathering. Or professionalism. You are not prepared to discuss science honestly. Back when I was the CIO of Technische Universität München, we had interns who collided atoms for fun in their spare time. Real physics. I have 100000 hours more time running quark experiments at the LHA than you, Einstein and Neil Degrasse Tyson combined.
 
Last edited:

Authentic Nouveau

Well-known member
So you can't discuss the virus. You need Fake checkers as a crutch to bludgeon people you can't stand.

Why are you making stuff up?

You know nothing about clinical virology. You have never even taken micro.

You were judging Some tucker dude on Fox

Judgmentalism.

Small rural Lutheran church pastor's wives are not prepared to do lab work and discuss.

From my Professional Psych credentials you are protecting your ego.

From medicine,
You don't understand this and have no clue how the Ammonium chloride and C18H26ClN3 operate inside the liposomes.

Since chloroquine inhibited SARS-CoV infection when added before or after infection, we hypothesized that another common lysosomotropic agent, NH4Cl, might also function in a similar manner. Ammonium chloride has been widely used in studies addressing endosome-mediated virus entry. Coincidently, NH4Cl was recently shown to reduce the transduction of pseudotype viruses decorated with SARS-CoV spike protein In an attempt to examine if NH4Cl functions similarly to chloroquine, we performed infection analyses in Vero E6 cells before (Fig. and after they were treated with various concentrations of NH4Cl. In both cases, we observed a 93–99% inhibition with NH4Cl at ≥ 5 mM. These data indicated that NH4Cl (≥ 5 mM) and chloroquine (≥ 10 μM) are very effective in reducing SARS-CoV infection. These results suggest that effects of chloroquine and NH4Cl in controlling SARS CoV infection and spread might be mediated by similar mechanism(s).

I won't go into the transport vehicle since you are not prepared to discuss science.

Fauchi is not completely ignorant. He is deceptive. You missed the 2 lines where he mentioned the width of the spectrum.

For C18H26ClN3O
Has more than 1 function.

As a lysosomotropic agent, hydroxychloroquine raises intralysosomal pH, impairing autophagic protein degradation; hydroxychloroquine-mediated accumulation of ineffective autophagosomes may result in cell death in tumor cells reliant on autophagy for survival.

I can see right thru your political games and science outsider political agenda.
Notice to left wingers. This is a science topic. Not a political product.
 
Top